Your Email Address:

First Name:




H. Pylori/Halitosis Connection

Everything related with bad breath can be found here. Everything about products, research, news about bad breath......
girlie girl
Advanced
Posts: 158
Joined: Wed Apr 04, 2007 2:44 pm
Location: United States

H. Pylori/Halitosis Connection

Post by girlie girl »

I plan on trying the triple therapy and will be using probiotics before I start and well after I finish. This was an interesting article I found on H. Pylori treatment and probiotics. Just FYI...

Probiotic Yogurt May Help Eradicate H. pylori Infection

http://www.medscape.com/viewarticle/530055


TeamZissou
Advanced
Posts: 143
Joined: Mon Nov 10, 2008 11:01 pm

Post by TeamZissou »

Hey girlie girl,

Do you know which combination of antibiotics and PPI you plan to try? I think there are a few different options.
User avatar
DRASTIC
Sheriff
Posts: 432
Joined: Sun Jul 06, 2008 11:35 am

Post by DRASTIC »

Girlie girl there is definately a connection.


Antibiotics are the Best Way to Fight Ulcers ???
Bacteria are the most likely cause of sores in stomach, duodenal lining.
by Gordon Slovut
Health & Fitness – Health Notebook
Star Tribune – Thursday, April 17, 1997




[ Note: Australian gastroenterologist Barry Marshall, M.D. and pathologist J. Robbin Warren proposed their theory for the bacterial cause of peptic ulcers in 1983. The bacterial cause of gastric ulcers in pigs was known in 1952. ]



--------------------------------------------------------------------------------

If you're one of the 5 million Americans with duodenal ulcers, you aren't, as you may believe, the victim of excess stomach acid, too much coffee, fried food or a cement–headed boss.

You are most likely the victim of a spiral–shaped bacteria, Helicobacter pylori.

The bug lives in the lining of your stomach, and washes down into the upper bulb of the duodenum, the first part of the small intestine where most ulcers occur. There it gnaws at the lining, initiating a painful ulcer, and somehow signals the stomach to produce more hydrochloric acid and more pepsin, a digestive enzyme. The pain of an ulcer can be relieved by eating.

Half of adults older than 60 have H. pylori in their bodies, but only a small percent of them develop ulcers. Among younger people, only 5 to 10 percent have H. pylori infections, and far fewer have ulcers.

It is not known why some people develop ulcers from the bug and others don't.

Germs hide in stomach lining
One good thing about H. pylori: It can be wiped out with a two– to three–week course of any of five or six antibiotics, which cost, on average, from $100 to $150 per treatment.
One bad thing: H. pylori is hard to reach in the lining, so the antibiotics have to be taken daily for two weeks even though the painful symptoms of ulcers disappear fairly soon after treatment starts.

Most of the other 10 percent of ulcers occur in people taking large doses of anti-inflammatory drugs, such as aspirin and ibuprofen, for extended periods. The drugs tend to erode the wall of the intestine.

Those ulcers almost always clear up when people take stomach-soothing drugs such as Zantac and stop taking aspirin or ibuprofen.

Not for executives only
For many years doctors prescribed a bland diet for ulcers on the theory that fried and spicy foods stirred up excess stomach acid, which then ate holes in the walls of the stomach and duodenum. They urged patients to avoid coffee and cigarettes.
They also thought that stress caused ulcers. Some thought there was an ulcer personality, people who were harried or worried too much.

"It turns out," said Dr. Robert Ganz, a Minneapolis gastroenterologist, "that diet has absolutely nothing to do with ulcers and that ulcers are much more common in people in lower socioeconomic levels than in people in upper socioeconomic levels. Alcohol has nothing to do with ulcers. Smoking probably has nothing to do with it either."

He said it is only a coincidence that both smoking and ulcers are more common among poor people than among the middle–class.

Bland diet and relaxation as treatment were replaced by a more effective, rational method – antacids to neutralize or suppress stomach acid.

"When Zantac [and other acid-suppressing drugs] came along, it almost wiped out ulcer surgery, " Ganz said.

Scientist swallows bugs, gets sick
The antacid drugs were, and still are, effective. But they don't cure the disease. As soon as people go off the antacids, the ulcers have the potential to come back.
The reason is simple, according to Dr. John Allen, another Minneapolis gastroenterologist. H. pylori is still alive and well in the lining of the stomach, he said.

The saga of H. pylori and ulcers began in 1982 when two Australian researchers, Drs. Barry Marshall and Robin Warren, noticed H. pylori in the lining of the stomach of people with gastritis, inflammations which include peptic ulcers.

To prove that H. pylori wasn't just an innocent bystander, Marshall swallowed a teaspoonful of culture containing H. pylori. He developed hunger upon awakening, irritability and bad breath, all symptoms of gastritis.

Marshall and Warren subsequently established that H. pylori infection causes ulcers in the stomach and the duodenum. It turned out that the bug seemed to cause about half of stomach ulcers, and 90 percent of the much more common duodenal ulcers.

Gnawing pain?
The rest is medical history.
In the early 1990s some gastroenterologists started prescribing antibiotics, usually along with other antiulcer drugs, wiping out both the ulcers and the infections, Allen said.

Now doctors are worried that ulcers may make a comeback because some people fail to take their prescriptions as directed, stopping when the symptoms disappear, but before the bug has been wiped out.

That can allow some live bacteria in the stomach to return stronger than ever and resistant to antibiotics, Allen said.

The most common symptom of an ulcer is a gnawing or burning pain in the abdomen between the navel and the lower part of the breastbone. It most often occurs between meals or in the early morning and can last from a few minutes to a few hours. It usually is relieved by eating food or antacids.

Because the symptoms can be produced by something else, doctors usually have to use X–rays or an examination through a flexible, lighted tube to make the diagnosis.


What about the future?
"There will be a vaccine coming," Allen said. "People are working on it right now."



Star Tribune graphic by Michael Godfrey

The Ulcer "bug"
At some point in their lives, about one in 10 Americans will develop ulcers, the painful sores that appear in the lining of the duodenum or the stomach. Recent research has shown that most sores are caused by a spiral–shaped bacteria called Helicobacter pylori. Contrary to previous medical beliefs that ulcers were lifelong problems that should be treated with a bland diet and antacid medication, physicians now prescribe a two-week course of antibiotics to eliminate most ulcers.

Any questions or comments?
Call Star Tribune medical writer Gordon Slovut at 673-9083.
Please leave your name and telephone number.


--------------------------------------------------------------------------------


Ulcer Bug is Stubborn, Pervasive
by Jane E. Brody
Your Health — Star Tribune
Personl Health — Sunday, June 29, 1997

Helicobacter pylori, now emerging as the most likely culprit in ulcers, is difficult to diagnose and treatment often requires a combination of antibiotics and other medications to beat it.



--------------------------------------------------------------------------------

Could a person catch ulcers from a housefly? As preposterous as that might seem, it could happen, at least indirectly.

About 90 percent of ulcers are now known to be caused by a slender, spiral–shaped bacterium, Helicobacter pylori, or H. pylori. The resilient organism, found in the stomachs of one fourth of American adults, is believed to spread from person to person by food or water contaminated by fecal matter.

Microbiologists at St. Elizabeth's Medical Center in Boston recently demonstrated that the common housefly can become a reservoir of H. pylori, carrying the organism on its skin and in its intestinal tract and passing the bacterium on in its excretions.

One does not have to be a scientist to envision a likely mode of transmission. Houseflies lay eggs, develop and feed on excrement — human or otherwise — then often land on unprotected food, where they might deposit the troublesome organism and pass it along to an unsuspecting consumer.

If that mode of transmission is correct, it would partly explain why H. pylori infection is most common in poor countries. Indoor plumbing, refrigeration and modern sanitation are often lacking, and H. pylori infection is nearly universal.

A Common Bug

How H. pylori is transmitted is only one of several unsolved mysteries about a bacterium that should become as familiar to people as E. coli, salmonella and pneumococcus. For one thing, scientists are still not sure exactly how H. pylori causes an ulcer, although they know how it is able to survive and flourish in the hostile acid environment of the stomach.

But the most pressing question is why, when so many people harbor the organism, often for their entire lives, do only a few develop ulcers? And why do even fewer develop two forms of stomach cancer that are also attributed to H. pylori infection? One strain of the organism has a gene that renders it more virulent than other strains. But is that the whole answer? Are human factors also involved?

There is no simple way to predict who is likely to get sick from an H. pylori infection, so people could be treated to eliminate the organism before illness strikes.

Does Stress Play a Role?

Although discovery of H. pylori has prompted experts to discount stress as a cause of ulcers, might stress–induced changes in body chemistry explain why some people are susceptible and others are resistant to ulcers caused by the bacterium?

Then there is the treatment dilemma: the inability so far to find a simple way to cure an H. pylori infection. Three or four drugs taken simultaneously are best able to knock out the organism, but the more complicated, costly and unpleasant the treatment regimen, the less likely people are to follow it and be cured.

Thanks to the discovery of H. pylori 15 years ago by Australian scientists Barry Marshall and J. Robin Warren, most people, who develop the symptoms of an ulcer can be spared the constant threat of recurrence once they are treated with appropriate antibiotics.

They no longer have to gobble antacids forever or live on a bland diet, avoiding all spices, alcohol and coffee to squelch the pain that arises in the upper abdomen whenever their stomachs are empty or they consume irritating foods. And although reducing stress is always a good idea, ulcer or no ulcer, relaxation therapy is not essential to keeping the distressing ailment at bay.

There are several ways to diagnose an H. pylori infection. The simplest and least expensive is a blood test that can detect antibodies to H. pylori. But the test cannot distinguish between a current active infection and a past one. A second more expensive blood test may be needed to be certain of the diagnosis.

A Breath Test

Amore costly but also more precise method is the recently approved urea breath test. The patient consumes a small amount of urea that has a special form of carbon. If H. pylori bacteria are present in the stomach, a short while later the patient will exhale carbon dioxide that has the special carbon.

With the tests doctors usually can avoid having to insert a fiber–optic tube into the stomach to examine the stomach lining and to take a tissue sample to test for H. pylori. Although it is the most accurate test, it is also the most expensive and discomforting, and it must be administered by a specialist in gastroenterology.

A test not yet approved relies on detecting the genes of the bacteria in dental plaque or stool samples. It is quick and painless, and it can identify the particular strain of the organism.

Experts recommend testing anyone who has a new or recurrent stomach or duodenal ulcer, including those who regularly take nonsteroidal anti–inflammatory drugs such as ibuprofen and aspirin, which are known produce ulcers in some people But people with chronic acid digestion need not be tested because treatment to eradicate H. pylori infection, if found, has not been shown to relieve the symptoms.

No Easy Treatment

Anyone with an active ulcer or a healed ulcer who is found to harbor H. pylori should be treated to eradicate the organism. But the bacterium does not go down without a good fight. No one drug is fully effective, and the organism readily develops resistance to antibiotics. Thus is important to hit it hard and effectively with the first round of treatment.

There are several treatment options, none of them easy or pleasant. All involve a two–week regimen that combines one or two antibiotics and a substance that coats stomach lesions or a substance that inhibits secretion of stomach acid or both. The cost of medication ranges from $30 to $200.

Two four–drug regimens that include the antibiotics metronidazole and tetracycline with bismuth ( Pepto–Bismol ), which coats the stomach, and omeprazole ( Prilosec ), an acid inhibitor, are the most effective, eradicating the organism in 95 percent of cases.

Although the drugs cost more than $100, and the treatment is complex, it pays to follow it closely if you want to be cured. Side effects, which may include diarrhea, taste disturbances, nausea and black stools, disappear when the treatment is completed.

— Jane Brody writes about health and medicine for the New York Times.



--------------------------------------------------------------------------------


U.S.A. Today — Life
girlie girl
Advanced
Posts: 158
Joined: Wed Apr 04, 2007 2:44 pm
Location: United States

Post by girlie girl »

TeamZissou wrote:Hey girlie girl,

Do you know which combination of antibiotics and PPI you plan to try? I think there are a few different options.
I am using...
-amoxicillin
-clarithromycin
-omeprazole

for 2 weeks.

As I am taking them, I will be using probiotics, yogurt, & K-12 for the mouth. I have not gotten the drugs yet, but they are on order. Will post as I go.
Snobuni
Sheriff
Posts: 383
Joined: Tue Apr 22, 2008 11:53 am

Post by Snobuni »

Hey Girlie Girl,

I'm doing the same 'cept with tetracycline amd metro instead of amoxicillin and clarithro. We should compare notes on how it's going!! :D

When do you plan on starting?
User avatar
DRASTIC
Sheriff
Posts: 432
Joined: Sun Jul 06, 2008 11:35 am

Post by DRASTIC »

Hi Girlie Girl and Snobuni,

Did you guys do a test to confirm h. pylori or did you do a home test??????????

Drastic
girlie girl
Advanced
Posts: 158
Joined: Wed Apr 04, 2007 2:44 pm
Location: United States

Post by girlie girl »

Snobuni wrote:Hey Girlie Girl,

I'm doing the same 'cept with tetracycline amd metro instead of amoxicillin and clarithro. We should compare notes on how it's going!! :D

When do you plan on starting?
Snobuni,

This will be very interesting. I know people think we are crazy for doing this, but if we don't try we will never know. I am a nurse and I feel that is totally safe if you are a healthy individual without any serious health deficits. I am waiting on my shipment and then I will start. I promise I will keep you updated.
girlie girl
Advanced
Posts: 158
Joined: Wed Apr 04, 2007 2:44 pm
Location: United States

Post by girlie girl »

DRASTIC wrote:Hi Girlie Girl and Snobuni,

Did you guys do a test to confirm h. pylori or did you do a home test??????????

Drastic
No, I didn't, but the tests aren't very reliable. Many Gastrologist will treat, without test confirmation, based on symptoms. I have many "vague" abdominal symptoms that I have had since middle school and I truly believe I have this condition. I know that whenever you take anitbiotics you should always counteract them with probiotics (i.e. yogurt) to keep balance in check between good bacteria and yeast. I'm not sure that this anitbiotic treatment will permanently rid my mouth of these bacteria, but maybe I will get abdominal relief.
User avatar
DRASTIC
Sheriff
Posts: 432
Joined: Sun Jul 06, 2008 11:35 am

Post by DRASTIC »

Hi Girlie Girl and Snobuni, I finally managed to get my new doctor to ok the stool h. pylori test today. I will hand in my sample tomorrow. NHS are so slow. I didnt do any of the hometest either because they can be unreliable. Have you started as yet? Any of you started the antibiotic therapy? My doctor didnt want to do a test. What a nut!!! He was more like OH have you taken over the counter meds for the indigestion did they work? I said to him, I would like to do the h. pylori test because I am worried. He then said ok.

Teamzissou, How are you at the moment? Are you on antibiotic therapy? How is that going so far? Any change?

At times like these I wish I had a family member who was doctor so I get some antibiotic without bothering these stupid quack doctors-Who tell you to take over the counter meds and then come back in 2 weeks. I could have told myself that in the mirror this morning instead of wasting 30 minutes of my day getting there, waiting and getting back in the cold.

ANYWAYS< one good thing is I got to do the h. pylori test.


Drastic
Snobuni
Sheriff
Posts: 383
Joined: Tue Apr 22, 2008 11:53 am

Post by Snobuni »

Drastic,

I took a home blood test which was negative, but these can be unreliable. I'm planning on starting on the 1st or 2nd of January (just trying to enjoy xmas as much as I can, eating and drinking whatever I like at the mo!) My course is for 2 weeks, I'll let you know if it has any long term effects when I've finished.

I've an ENT appointment on the 24th, so I'm hoping that if my bb is going to come back, it'll happen before then.

Girlie Girl,

How long is your treatment for, 1 or 2 weeks? Good luck! :)
girlie girl
Advanced
Posts: 158
Joined: Wed Apr 04, 2007 2:44 pm
Location: United States

Post by girlie girl »

I am going to do the 2 week treatment. Good luck to you too!
User avatar
DRASTIC
Sheriff
Posts: 432
Joined: Sun Jul 06, 2008 11:35 am

Post by DRASTIC »

HI Girlie Girl and Snobuni,

Good luck when you start you therapy. All the best.


Do you plan to take manuka honey as well while on your therapy. i hear its good for h. pylori?

Drastic
halihope
Master
Posts: 250
Joined: Mon Apr 28, 2008 9:30 pm

Post by halihope »

Snobuni
where did you get the home blood test to test for h.pylori? I don't have any of the symptoms but would like to do the test anyhow.
Snobuni
Sheriff
Posts: 383
Joined: Tue Apr 22, 2008 11:53 am

Post by Snobuni »

Hey Halihope,

Here's the link for the blood test,

http://www.cambridge-nutritional.com/Sc ... product=26

Snobuni
TeamZissou
Advanced
Posts: 143
Joined: Mon Nov 10, 2008 11:01 pm

Post by TeamZissou »

Good luck when you start Girlie Girl and Snobuni. I'm going to wait until after the holiday to start as well, to be able to eat whatever and possibly drink etc. I'm going to do metro, clarithromycin, and a PPI for two weeks. So it looks like we have three different combinations here between us. It will be interesting to see how they work.

Good luck to you as well Drastic with the HP testing. It may be worth giving the antibiotics a try even if its negative, just incase the cures from this treatment were from killing off another bacteria, and not HP.
Post Reply Previous topicNext topic