Krespi gave me a reply to newsletter
Posted: Wed Sep 10, 2008 6:58 pm
I think Krespi is the guy that is honest and at least does something. I like him and also Yehuda even though that Yehuda relies heavily on halitophobia.
I got reply from Krespi office
Here is the exerpt
Dr. Krespi is presenting 2 important topics at this years American Academy of Otolaryngology in Chicago from Sept. 20th thru Sept 24th. See announcements below. Also attached is a file of the publications that have been made.
Please contact me via e-mail or Dr. Krespi at [email protected]
if you would like more information.
Kimberly A. Gross
Assistant to Yosef P. Krespi, MD
Chairman, Department of Otolaryngology
St. Luke's-Roosevelt Hospital Center
Head and Neck Surgical Group
425 W. 59th St., 10th Fl
New York, NY 10019
212-262-2929
(F)212-523-8168
Halitosis: A Rational Approach to Evaluation and Treatment
The evaluation of halitosis is rarely discussed in literature. However, this disorder can be a crippling social problem affecting business and personal relationships. Those afflicted with halitosis often receive inadequate care from healthcare providers because of propagation of myths regarding its ...
Presenters: Yosef P Krespi MD
Day: September 23, Tuesday
Time: 4:15p - 5:15p
Program: Instruction Courses
Room: E450A
Abstract: The evaluation of halitosis is rarely discussed in literature. However, this disorder can be a crippling social problem affecting business and personal relationships. Those afflicted with halitosis often receive inadequate care from healthcare providers because of propagation of myths regarding its causes and ignorance of effective treatments. The standard dental treatments and mouthwashes often recommended are transient measures that provide only temporary relief because they do not address the underlying cause of the disorder. The instructors will develop a rational, effective approach to the care of the patient with halitosis. Etiologies of halitosis including upper aerodigestive tract pathology, medical conditions, and drug side effects will be presented. The role of the oral cavity as the causative site of halitosis in most patients will be stressed. Particularly, the role of volatile sulfur compound (VSC) in producing bacteria that colonizes the base of the tongue will be expanded upon. The Halimeter, a device that provides quantitative determination of VSC levels will be demonstrated. Treatment options aimed at specific causative sites will be presented.
Educational Objectives: (1) Understand the varied causes of halitosis. (2) Learn the various diagnostic and treatment options.
Relevance & Purpose: This course will discuss the common etiologies of halitosis, including upper aerodigestive tract pathology, medical conditions, and drug side effects. The role of volatile sulfur compound (VSC) in producing bacteria that colonizes the base of the tongue will be emphasized. The use of the Halimeter, a device that provides quantitative determination of VSC levels, will be demonstrated. At the end of the course a comprehensive flow chart showing the diagnostic steps and treatment options for halitosis will be presented.
Key Points: The evaluation of halitosis is rarely discussed in the literature. However, this disorder can be a crippling social problem affecting business and personal relationships. Those afflicted with halitosis often receive inadequate care from health care providers because of propagation of myths regarding its causes and ignorance of effective treatments. The standard dental treatments and mouthwashes often recommended are transient measures which provide only temporary relief because they do not address the underlying cause of the disorder. The instructors will develop a rational, effective approach to the care of the patient with halitosis. Etiologies of halitosis including upper aerodigestive tract pathology, medical conditions, and drug side effects will be presented. The role of the oral cavity as the causative site of halitosis in most patients will be stressed. Particularly, the role of volatile sulfur compound (VSC) producing bacteria colonizing the base of tongue will be expanded upon. The Halimeter, a device that provides quantitative determination of VSC levels will be demonstrated. Treatment options aimed at specific causative sites will be presented. Halitosis can be a crippling social problem affecting business and personal relationships. Common etiologies of halitosis including upper aerodigestive tract pathology, medical conditions, and drug side-effects will be discussed The role of volatile sulfur compound (VSC) producing bacteria colonizing the base of tongue will be emphasized. The use of the Halimeter, a device that provides quantitative determination of VSC levels will be demonstrated.
References: Loesche WJ. The effects of antimicrobial mouthrinses on oral malodor and their status relative to US Food and Drug Administration regulations. Quintessence International. 30(5):311-8, 1999 May. Rosenberg M. Kozlovsky A. Wind Y. Mindel E. Self-assessment of oral malodor 1 year following initial consultation. Quintessence International. 30(5):324-7, 1999 May.
***********************************************************************
Tonsillolith: Not Just a Stone But a Living Biofilmshow in clusters
To study the morphology and activity of tonsilloliths ex vivo, using confocal microscopy and microelectrodes. Understanding the similarities of tonsilloliths to dental biofilm by demonstrating oxygen respiration, de-nitrification, and acid production. ... Tonsilloliths exhibit biofilm structure and the formation ...
Presenters: Yosef P Krespi MD (presenter); Anil Arora, MD; Mark Longwell; Laura Nistico, Phd; Luanne Hall-Stoodley, PhD; Dirk de Beer; Paul Stoodley, PhD
Day: September 23, Tuesday
Time: 08:00a - 9:30a
Program: Translational & Basic Orals
Kimberly A. Gross
Assistant to Yosef P. Krespi, MD
Chairman, Department of Otolaryngology
St. Luke's-Roosevelt Hospital Center
Head and Neck Surgical Group
425 W. 59th St., 10th Fl
New York, NY 10019
212-262-2929
(F)212-523-8168
Kimberly A. Gross
Assistant to Yosef P. Krespi, MD
Chairman, Department of Otolaryngology
St. Luke's-Roosevelt Hospital Center
Head and Neck Surgical Group
425 W. 59th St., 10th Fl
New York, NY 10019
212-262-2929
(F)212-523-8168
Objective
To study the morphology and activity of tonsilloliths ex vivo, using confocal microscopy and microelectrodes. Understanding the similarities of tonsilloliths to dental biofilm by demonstrating oxygen respiration, de-nitrification and acidification on exposure to sucrose.
Materials and Methods
Tonsilloliths were harvested from several patients and sent to the laboratory under sterile conditions. The tonsilloliths were examined by confocal microscopy to determine the presence and distribution of bacteria. Microelectrodes (dissolved oxygen, nitrous oxide, and pH) were used to measure the rates of aerobic/anaerobic respiration and acid production, respectively, when exposed to saliva (10%) following addition of sucrose and fluoride.
Results
Morphologically, tonsilloliths were similar to dental-plaque biofilms, containing “corn-cob” structures, filaments and cocci. Microelectrodes showed that the microorganisms respired both oxygen and nitrate in physiological concentrations. The oxygen concentration in the center of the tonsillolith (500 microns) was depleted to approximately 1/10th of that of the overlying fluid. The addition of 10% sucrose resulted in the production of acid within the tonsillolith by dropping the pH from 7.3 to 5.8 at a depth of 200 microns. On addition of fluoride (1000 pm) the pH was raised back to 6.1 suggesting that the fluoride was suppressed acid fermentation in the presence of sucrose. The data showed stratification, oxygen respiration near the top, de-nitrification slightly lower and acidification towards to bottom. The tonsillolith therefore has stratified layers, similar to dental (and other) biofilms. The depletion of oxygen and acid production following addition of sucrose may allow the proliferation of anaerobic / acidophilic bacteria within the tonsillolith. Fluoride suppresses acid production in the presence of sucrose.
Conclusions
Tonsilloliths exhibit biofilm structure and the formation of chemical gradients through physiological activity. While complete or intracapsular tonsillectomy is an option for treating chronic cryptic infections, understanding the morphology and biofilm characteristics of tonsilloliths may stimulate scientists in using limited or non-surgical remedies in treating cryptic tonsillitis in the future.
I got reply from Krespi office
Here is the exerpt
Dr. Krespi is presenting 2 important topics at this years American Academy of Otolaryngology in Chicago from Sept. 20th thru Sept 24th. See announcements below. Also attached is a file of the publications that have been made.
Please contact me via e-mail or Dr. Krespi at [email protected]
if you would like more information.
Kimberly A. Gross
Assistant to Yosef P. Krespi, MD
Chairman, Department of Otolaryngology
St. Luke's-Roosevelt Hospital Center
Head and Neck Surgical Group
425 W. 59th St., 10th Fl
New York, NY 10019
212-262-2929
(F)212-523-8168
Halitosis: A Rational Approach to Evaluation and Treatment
The evaluation of halitosis is rarely discussed in literature. However, this disorder can be a crippling social problem affecting business and personal relationships. Those afflicted with halitosis often receive inadequate care from healthcare providers because of propagation of myths regarding its ...
Presenters: Yosef P Krespi MD
Day: September 23, Tuesday
Time: 4:15p - 5:15p
Program: Instruction Courses
Room: E450A
Abstract: The evaluation of halitosis is rarely discussed in literature. However, this disorder can be a crippling social problem affecting business and personal relationships. Those afflicted with halitosis often receive inadequate care from healthcare providers because of propagation of myths regarding its causes and ignorance of effective treatments. The standard dental treatments and mouthwashes often recommended are transient measures that provide only temporary relief because they do not address the underlying cause of the disorder. The instructors will develop a rational, effective approach to the care of the patient with halitosis. Etiologies of halitosis including upper aerodigestive tract pathology, medical conditions, and drug side effects will be presented. The role of the oral cavity as the causative site of halitosis in most patients will be stressed. Particularly, the role of volatile sulfur compound (VSC) in producing bacteria that colonizes the base of the tongue will be expanded upon. The Halimeter, a device that provides quantitative determination of VSC levels will be demonstrated. Treatment options aimed at specific causative sites will be presented.
Educational Objectives: (1) Understand the varied causes of halitosis. (2) Learn the various diagnostic and treatment options.
Relevance & Purpose: This course will discuss the common etiologies of halitosis, including upper aerodigestive tract pathology, medical conditions, and drug side effects. The role of volatile sulfur compound (VSC) in producing bacteria that colonizes the base of the tongue will be emphasized. The use of the Halimeter, a device that provides quantitative determination of VSC levels, will be demonstrated. At the end of the course a comprehensive flow chart showing the diagnostic steps and treatment options for halitosis will be presented.
Key Points: The evaluation of halitosis is rarely discussed in the literature. However, this disorder can be a crippling social problem affecting business and personal relationships. Those afflicted with halitosis often receive inadequate care from health care providers because of propagation of myths regarding its causes and ignorance of effective treatments. The standard dental treatments and mouthwashes often recommended are transient measures which provide only temporary relief because they do not address the underlying cause of the disorder. The instructors will develop a rational, effective approach to the care of the patient with halitosis. Etiologies of halitosis including upper aerodigestive tract pathology, medical conditions, and drug side effects will be presented. The role of the oral cavity as the causative site of halitosis in most patients will be stressed. Particularly, the role of volatile sulfur compound (VSC) producing bacteria colonizing the base of tongue will be expanded upon. The Halimeter, a device that provides quantitative determination of VSC levels will be demonstrated. Treatment options aimed at specific causative sites will be presented. Halitosis can be a crippling social problem affecting business and personal relationships. Common etiologies of halitosis including upper aerodigestive tract pathology, medical conditions, and drug side-effects will be discussed The role of volatile sulfur compound (VSC) producing bacteria colonizing the base of tongue will be emphasized. The use of the Halimeter, a device that provides quantitative determination of VSC levels will be demonstrated.
References: Loesche WJ. The effects of antimicrobial mouthrinses on oral malodor and their status relative to US Food and Drug Administration regulations. Quintessence International. 30(5):311-8, 1999 May. Rosenberg M. Kozlovsky A. Wind Y. Mindel E. Self-assessment of oral malodor 1 year following initial consultation. Quintessence International. 30(5):324-7, 1999 May.
***********************************************************************
Tonsillolith: Not Just a Stone But a Living Biofilmshow in clusters
To study the morphology and activity of tonsilloliths ex vivo, using confocal microscopy and microelectrodes. Understanding the similarities of tonsilloliths to dental biofilm by demonstrating oxygen respiration, de-nitrification, and acid production. ... Tonsilloliths exhibit biofilm structure and the formation ...
Presenters: Yosef P Krespi MD (presenter); Anil Arora, MD; Mark Longwell; Laura Nistico, Phd; Luanne Hall-Stoodley, PhD; Dirk de Beer; Paul Stoodley, PhD
Day: September 23, Tuesday
Time: 08:00a - 9:30a
Program: Translational & Basic Orals
Kimberly A. Gross
Assistant to Yosef P. Krespi, MD
Chairman, Department of Otolaryngology
St. Luke's-Roosevelt Hospital Center
Head and Neck Surgical Group
425 W. 59th St., 10th Fl
New York, NY 10019
212-262-2929
(F)212-523-8168
Kimberly A. Gross
Assistant to Yosef P. Krespi, MD
Chairman, Department of Otolaryngology
St. Luke's-Roosevelt Hospital Center
Head and Neck Surgical Group
425 W. 59th St., 10th Fl
New York, NY 10019
212-262-2929
(F)212-523-8168
Objective
To study the morphology and activity of tonsilloliths ex vivo, using confocal microscopy and microelectrodes. Understanding the similarities of tonsilloliths to dental biofilm by demonstrating oxygen respiration, de-nitrification and acidification on exposure to sucrose.
Materials and Methods
Tonsilloliths were harvested from several patients and sent to the laboratory under sterile conditions. The tonsilloliths were examined by confocal microscopy to determine the presence and distribution of bacteria. Microelectrodes (dissolved oxygen, nitrous oxide, and pH) were used to measure the rates of aerobic/anaerobic respiration and acid production, respectively, when exposed to saliva (10%) following addition of sucrose and fluoride.
Results
Morphologically, tonsilloliths were similar to dental-plaque biofilms, containing “corn-cob” structures, filaments and cocci. Microelectrodes showed that the microorganisms respired both oxygen and nitrate in physiological concentrations. The oxygen concentration in the center of the tonsillolith (500 microns) was depleted to approximately 1/10th of that of the overlying fluid. The addition of 10% sucrose resulted in the production of acid within the tonsillolith by dropping the pH from 7.3 to 5.8 at a depth of 200 microns. On addition of fluoride (1000 pm) the pH was raised back to 6.1 suggesting that the fluoride was suppressed acid fermentation in the presence of sucrose. The data showed stratification, oxygen respiration near the top, de-nitrification slightly lower and acidification towards to bottom. The tonsillolith therefore has stratified layers, similar to dental (and other) biofilms. The depletion of oxygen and acid production following addition of sucrose may allow the proliferation of anaerobic / acidophilic bacteria within the tonsillolith. Fluoride suppresses acid production in the presence of sucrose.
Conclusions
Tonsilloliths exhibit biofilm structure and the formation of chemical gradients through physiological activity. While complete or intracapsular tonsillectomy is an option for treating chronic cryptic infections, understanding the morphology and biofilm characteristics of tonsilloliths may stimulate scientists in using limited or non-surgical remedies in treating cryptic tonsillitis in the future.