hypothroidism, hormonal imbalance, metabolic disorder = bb?
Posted: Fri Apr 06, 2012 12:52 am
Looking at the post about low-carb diet causing bad breath, I am wondering if there are connections between hormone imbalance, hypothyroidism and metabolic disorder. Here's an interesting note from Wikipedia's page about hypothyroidism:
Basically, it's a chain effect. If you have hypothroidism, you have hormonal imbalance, metabolic disorder (chronic cortisol elevation which aids in fat, protein, carbohydrate metabolism).
"Stress is known to be a significant contributor to thyroid dysfunction: this can be environmental stress as well as lesser-considered homeostatic stress such as fluctuating blood sugar levels and immune problems. Moreover, adrenal stress's effect on thyroid function can be indirect, through its effects on blood sugar levels (dysglycemia),[29][30] but can also have more direct effects. Stress can cause hypothyroidism or reduced thyroid functioning through disrupting the HPA axis which down-regulates thyroid function,[31] reducing the conversion of T4 to T3,[32] weakening the immune system thus promoting autoimmunity,[33] causing thyroid hormone resistance,[34] and resulting in hormonal imbalances:[35] indeed, excess estrogen in the blood caused by chronic cortisol elevations (which reduce the liver's ability to clear excess estrogen[36]), can result in hypothyroid symptoms by decreasing levels of active T3.[37] Stress also affects thyroid functioning through the sympathetic nervous system.[38] Refugees from East Germany in a 1994 study who experienced chronic stress were found to have a very high rate of hypothyroidism or subclinical hypothyroidism, although not all refugees displayed clinical or behavioral symptoms associated with this reduced thyroid functioning.[39] TSH levels correlate positively with physiological stress."
Basically, it's a chain effect. If you have hypothroidism, you have hormonal imbalance, metabolic disorder (chronic cortisol elevation which aids in fat, protein, carbohydrate metabolism).
"Stress is known to be a significant contributor to thyroid dysfunction: this can be environmental stress as well as lesser-considered homeostatic stress such as fluctuating blood sugar levels and immune problems. Moreover, adrenal stress's effect on thyroid function can be indirect, through its effects on blood sugar levels (dysglycemia),[29][30] but can also have more direct effects. Stress can cause hypothyroidism or reduced thyroid functioning through disrupting the HPA axis which down-regulates thyroid function,[31] reducing the conversion of T4 to T3,[32] weakening the immune system thus promoting autoimmunity,[33] causing thyroid hormone resistance,[34] and resulting in hormonal imbalances:[35] indeed, excess estrogen in the blood caused by chronic cortisol elevations (which reduce the liver's ability to clear excess estrogen[36]), can result in hypothyroid symptoms by decreasing levels of active T3.[37] Stress also affects thyroid functioning through the sympathetic nervous system.[38] Refugees from East Germany in a 1994 study who experienced chronic stress were found to have a very high rate of hypothyroidism or subclinical hypothyroidism, although not all refugees displayed clinical or behavioral symptoms associated with this reduced thyroid functioning.[39] TSH levels correlate positively with physiological stress."